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Model Overview.
The Agilent 6545XT LC/Q-TOF Mass Spectrometer is a high-resolution analytical instrument used to separate, detect, and identify compounds in complex mixtures with excellent mass accuracy and sensitivity.
Model Details.
Specification2026-07-07T10:10:01+00:00
- Ultra High Performance Liquid Chromatography (UHPLC) system
- Quadrupole Time-of-Flight (Q-TOF) high-resolution mass analyzer
- In-spectrum Dynamic Range: 5 Orders
- MS Acquisition Rate: 50 spectra/second
- MS/MS Acquisition Rate: 30 spectra/second
- MS Mass Accuracy: <0.8 ppm RMS (positive & negative mode)
- MS/MS Mass Accuracy: <2 ppm RMS (positive & negative mode)
- TOF Mass Range: m/z 20–30,000
- Quadrupole Isolation Mass Range: m/z 20–4000
- TOF Resolution: >50,000 (FWHM at m/z 2,722)
- Polarity Switching Duty Cycle: 1.5 s
- Temperature Mass Stability: <1 ppm / 3°C
- Ventless Maintenance: VacShield Technology
Ion Sources Available2026-07-07T10:13:29+00:00
- Dual-AJS ESI (Electrospray Ionization)
- Dual-ESI
- Multimode (ESI + APCI)
- APCI
- GC/APCI
- NanoESI
Sensitivity2026-07-07T10:14:21+00:00
- MS Sensitivity: S/N > 500:1 (1 pg reserpine)
- MS/MS Sensitivity: S/N > 1500:1 (1 pg reserpine)
Software Platform2026-07-07T11:54:26+00:00
- Agilent MassHunter
- Supported Software Add-ons:
- MassHunter BioConfirm
- MassHunter VistaFlux
- Classifier
- Lipid Annotator
- Mass Profiler Professional
Application2026-07-07T11:55:42+00:00
The LC-MS is an advanced analytical instrument that combines Liquid Chromatography (LC) and Mass Spectrometry (MS) to separate, detect, and identify compounds in complex mixtures.
Capability of LC-MS2026-07-07T11:57:52+00:00
Analyzes complex mixtures by separating compounds and identifying them using mass-to-charge ratio (m/z).
Sample Requirement:
- Liquid/dissolved form
- 1–2 mL recommended
- Filtered before injection
- Compatible solvents: Water, Methanol, Acetonitrile
