The Agilent 6545XT Q-TOF LC/MS is a liquid chromatograph-quadrupole time-of-flight mass spectrometer. Combining with Agilent 1290 Infinity II LC system it delivers the highest level of efficiency. It is designed for untargeted sample analysis, and it delivers sensitivity, resolution, mass accuracy, isotopic fidelity, and speed in one measurement. This system can handle multiple workflows in biomolecules characterization, such as examining intact proteins, mapping peptide sequences or analyzing post-translational modifications. With design innovation specifically for large molecule analysis, the 6545XT LC/Q-TOF gives you accurate mass measurements down to low ppm levels. The instrument has a mass range that extends up to 30,000 m/z and the resolution of 50000. Optimizing your system for intact proteins is easy with SWARM autotune. This system accurately profile major and minor proteoforms with time-of-flight technology offering new levels of sensitivity and clarity to intact protein mass spectrometry.
|
Parameter |
Parameter |
| MS Accuracy, positive | <0.8 ppm RMS in 10 replicates |
| MS Accuracy, negative | <0.8 ppm RMS in 10 replicates |
| MS/MS Sensitivity | >1,500:1 ppm RMS in 10 replicates |
| MS/MS Accuracy, positive | <2.0 ppm RMS in 10 replicates |
| MS/MS Accuracy, negative | <2.5 ppm RMS in 10 replicates |
| Intact protein accuracy | <10 ppm RMS in 10 replicates |
| Mass resolving power | >50,000 FWHM at m/z 2,722 |
| Mass range | 50–30,000 m/z |
| Spectral acquisition rate, MS | 50 spectra/second |
| Spectral acquisition rate, MS/MS | 30 spectra/second |
Application – Single-molecule, Metabolomics, Proteomics, Intact Protein Analysis, Peptide Sequence Mapping
Charges-
| Services | Charges (For measurements only) in INR (₹) | ||
| (Per polarity per sample basis/measurement only) | KIIT group Users | Educational Institutes | Industry |
| LC (Extra charges @ 300/30min run) | 350 | 450 | 1050 |
| LCMS (≤15min) (Extra charges @ 300/30min run) | 450 | 600 | 1200 |
| LC-MS/MS (Extra charges @ 400/30min run) | 600 | 900 | 1800 |
| Metabolite Profiling (only MS) (Extra charges @ 500/30min run) | 3000 | 4000 | 9000 |
| Targeted Metabolite Profiling (MS/MS) (Extra charges @ 500/30min run) Standards to be provided by the user | 4500 | 6000 | 13500 |
| For any other specialized experiment and / or analysis, please contact [email protected] | |||
FIC name- Dr. Alok Kumar Panda
Assistant Professor
Mail Id- [email protected]
LCMS-faculty In-Charge
Name of the In-charge : Dr. Alok Kumar Panda
Designation : Assistant Professor
Contact details :[email protected]











